There's a little bug in this mod that I've experienced several different times, but I wanted to truly make sure this was a consistent bug, and it is.
If you're busy veinmining walls so enemies stop spawning on them, the smart cursor will sometimes hover over a vine tile. If you're holding alt+click, over the vine, the game will crash. This doesn't cause world corruption- at least not any that I've seen- but a game-crashing bug is still pretty significant.